Intravenous route

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  • Allows rapid and more predictable delivery of drugs.
  • In some drugs, allows higher doses than would be tolerated orally.
  • Bypasses first-pass metabolism.
  • Not depedent on gut function or muscle perfusion (cf. intramuscular route).
  • Allows administration of large volumes, e.g. intravenous fluids


  • Requires indwelling device with attendent complications associated with insertion.
  • Requires trained professional to administer drug.
  • Danger of extravasation.
  • Phlebitis if irritant drugs.
  • Risk of excessively rapid administration of certain drugs, e.g. intravenous fluids, gentamicin, frusemide, etc.

See Also