Sindbis virus causes sindbis fever (Pogosta disease in Finland, Ockelbo disease in Sweden, Karelian fever in Russia) in humans and the symptoms include arthralgia, rash and malaise. Transmission is by Culex spp. and Culiseta spp. mosquitoes with Grouse and migratory birds being the reservoir. It is most common in South and East Africa, Egypt, Israel, Philippines and parts of Australia year round and in northern Europe during August and September. It is an positive stranded RNA alphavirus.