Krueppel-like factor 15

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Krueppel-like factor 15 is a 416 amino acid transcriptional activator coded by the KLF15 gene at 3q21.3. An animal model exists that suggest its expression varies with diurnal rhythm and as it modulates ion channels it may have a role in explaining the diurnal variation in sudden cardiac death. It binds to an element of a voltage-gated chloride channel (CLCNKA) promoter.