LDHD

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Web Resources for LDHD


Genetic Databases
GENE database on LDHD
Online Mendelian Inheritance in Man (OMIM) on LDHD
Pharmacogenomics Knowledge Base (pharmGKB) on LDHD
Catalogue Of Somatic Mutations In Cancer (COSMIC) on LDHD
Genome information (GenomeNet, KEGG) on LDHD
SNP database on LDHD
Protein Knowledgebase (UniProtKB) on LDHD
Relevant Clinical Literature
Pubmed on LDHD
RCT with LDHD
Systematic reviews of LDHD
LDHD in N Eng J Med, Lancet, JAMA, BMJ
LDHD in Cochrane Collaboration
TRIP Database on LDHD
Google Scholar on LDHD
Bandolier on LDHD
UK Guidance
NHS Evidence on LDHD
Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)
Nice Guidance on LDHD
Prodigy Guidance on LDHD
Other Wikis
Medpedia on LDHD (Less technical, good quality control)
Wikipedia on LDHD (Less technical, ? quality control)

The gene LDHD codes for a 507 amino acid peptide believed to be mitochondrial D-lactate dehydrogenase (Lactate dehydrogenase D, DLD, EC:1.1.2.4)

  • Two isoforms
  • Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.
  • Catalyses (R)-lactate + 2 ferricytochrome c <=> pyruvate + 2 ferrocytochrome c.
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