Lactose

From Ganfyd

Common Name:Lactose

Other Names, such as IUPAC Name

C₁₂H₂₂O₁₁, (2R,3R,4S,5R,6R)-6-( hydroxymethyl )-5-[( 2S,3R,4S,5S,6R )-3,4,5- trihydroxy -6-( hydroxymethyl ) oxan-2-yl] oxy- oxane-2,3,4- triol

Biochemical Information

Molecular Structure

Lactose Molecule

PubChem on Lactose

CTD (Comparative Toxicogenomics Database) on Lactose

Chemical Information on Lactose

Protein Structural Information on Lactose

Biological Information (GenomeNet) on Lactose

Protein Knowledgebase (UniProtKB) on Lactose

Online Mendelian Inheritence in Man (OMIM) on Lactose

Important Issues in Man

Enjoyable sugar especially if you are a non-weaned infant

Data limitations

Relevant Clinical Literature

Pubmed on Lactose

RCT with Lactose   from Pubmed

Systematic reviews of Lactose   from Pubmed

Lactose in N Eng J Med, Lancet,JAMA, BMJ   from Pubmed

Lactose in Cochrane Collaboration   from Pubmed

Google Scholar on Lactose

Disaccharide formed from glucose and galactose. Commonly found in milk.

Lactase is the digestive enzyme needed to break lactose into its monosaccharide constituents for absorption. Levels decrease with age, so that the majority of the adult population is relatively lactase-deficient. Excess consumption can cause lactose intolerance, where undigested lactose is metabolised by gut flora. These metabolites have an osmotic effect and can cause abdominal discomfort, bloating, gas and diarrhoea. This effect is actually mimicked by lactulose, a semi-synthetic disaccharide which mediates its effect by a similar mechanism. If taken in sufficient quantities, xylitol and sorbitol can have a similar effect.