Lamivudine

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Contents

Introduction

Lamivudine is an antiretroviral used to treat both HIV-1 and HIV-2 infections. It also has activity against hepatitis B.

Clinical Use

Indications

In combination for HIV therapy

Administration

In adults 300 mg orally daily

Clinical Issues

Contra-indications

Cautions and Interactions

  • In moderate to severe renal impairment decreased clearance

Side effects

Special advice

Pharmacology

Nucleoside analogue.