Leflunomide

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Contents

Clinical Use

The drug is likely to be open to generic competition in 2011

Indications

Despite its predominantly immunosuppressive activity, may have activity against cytomegalovirus.[1]

Administration

Oral

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

  • Needs careful monitoring e.g. Liver function tests
  • Washout needed in case of serious adverse effect or change of treatment/contraception with colestyramine or activated charcoal

Pharmacology

References

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