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Lenisurad is an oral, once daily URAT1 inhibitor for use in gout. It should be used in combination with a xanthine oxidase inhibitor.


  • Risk of acute kidney injury when used alone
  • Cardiovascular safety questions

Side effects

  • Headache
  • Renal impairment
  • Gastroesophageal reflux disease
  • Possibly increase influenza risk !