ICD 10 code: G40.4
Relevant Clinical Literature
Wikipedia on Lennox-Gastaut syndrome (Less technical, ? quality control)
UpToDate® on Lennox-Gastaut syndrome (Technical, SUBSCRIPTION)
Lennox-Gastaut syndrome is a form of childhood onset severe epilepsy.
It is characterised by:
- Seizures usually before 4 years that are
- Very frequent-25 a day or more
- Refractory to treatment
- Wide variety of types
- Impaired intellectual functioning, information processing and/or behaviour.
- Developmental delay
- EEG shows diffuse slow spike waves (<3Hz) and bursts of fast (10Hz) waves during sleep. (first correlated in 1950 by William Gordon Lennox)
There are multiple causes (which may influence the usually poor prognosis):
- Brain malformations
- Brain damage
- Congenital and childhood central nervous system infection
- Genetic conditions.
- About 1 in 10,000 (5% of all childhood epilepsy)