Leriche's syndrome

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Named after René Leriche.[1] Robert Graham in England may have been the first to describe aorto-iliac occlusive disease in 1814.

A manifestation of atherosclerotic occlusive disease affecting the distal aorta, just above its bifurcation. Manifest as bilateral claudication, although in the original description, the exact phrase used was "extreme liability to fatigue" of the lower limbs (in distinction to intermittent claudication). Other features include erectile dysfunction, absent pulses in the groin and trophic changes of the lower limbs. Although not in the original description, back or buttock pain is also described in the context of the underlying pathology.