Levofloxacin

From Ganfyd

rINN: Levofloxacin

Pharmacological Information

Pharmacology Images

Levofloxacin Molecule

Web information on Levofloxacin

NHS Evidence on Levofloxacin

DrugBank on Levofloxacin

Relevant Clinical Literature

Pubmed on Levofloxacin

RCT with Levofloxacin

Systematic reviews of Levofloxacin

Levofloxacin in N Eng J Med, Lancet, JAMA, BMJ

Levofloxacin in Cochrane Collaboration

TRIP Database on Levofloxacin

Google Scholar on Levofloxacin

Bandolier on Levofloxacin

UK Guidance

SNOMED search

Nice Guidance on Levofloxacin

BNF-registration required
BNF for children-registration required

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)

Prodigy Guidance on Levofloxacin

Regulatory Literature

UK SPCs of medicines with marketing authorisation

EMEA search

FDA search

Other Literature

PubChem on Levofloxacin

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Other Wikis

Medpedia on Levofloxacin (Less technical, good quality control)

Wikipedia on Levofloxacin (Less technical, ? quality control)

Introduction

Clinical Use

Indications

Administration

Oral IV

Clinical Issues

Contraindications

• Myasthenia gravis (may precipitate initial diagnosis)

Adverse Effects

• Seizures (+/- predisposing condition)
• Tendonitis
• Arthropathy in immature animals - so avoided in children (except nalidixic acid) unless extenuating circumstances (only reversible musculoskeletal symptoms have been reported)
• Photosensitivity

Side effects

Special advice

Pharmacology