Lorcaserin

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Contents

Introduction

A selective 5-hydroxytryptamine 2C agonist in development for obesity as an appetite suppressant[1]

Clinical Use

Indications

Administration

Oral

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology

Might work in schizophrenia. Fifteen times more selective at 5-HT(2C) than 5-HT(2A) and 100 times more selective at 5-HT(2C) than 5-HT(2B). In rats at high doses it induces tumours.

References

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