Lutropin subunit beta

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Coded by the LHB gene at 19q13.32 it is the specific component of the luteinizing hormone heterodimer that results in spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Specific mutations result in ovulatory disorders, including infertility and male delayed puberty,infertility and hypogonadism. There is some normal polymorphism which may have significance in polycystic ovary syndrome and borderline infertility.

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