An organism that causes a form of filariasis that in man usually produces subclinical infection with microfilarial periodicity peaking in peripheral blood soon after sunrise.
- Occasionally associated with:
Is is endemic in central and western Africa, with an intermediate midge (culicoides spp.) vector. Its infectivity is reduced by control measures targetted at its bacterial endosymbiont wolbachia such as 6 weeks of doxycycline 200mg daily.
- ↑ Keiser PB, Coulibaly Y, Kubofcik J, Diallo AA, Klion AD, Traoré SF, Nutman TB. Molecular identification of Wolbachia from the filarial nematode Mansonella perstans. Molecular and biochemical parasitology. 2008 Aug; 160(2):123-8.(Link to article – subscription may be required.)
- ↑ Coulibaly YI, Dembele B, Diallo AA, Lipner EM, Doumbia SS, Coulibaly SY, Konate S, Diallo DA, Yalcouye D, Kubofcik J, Doumbo OK, Traore AK, Keita AD, Fay MP, Traore SF, Nutman TB, Klion AD. A randomized trial of doxycycline for Mansonella perstans infection. The New England journal of medicine. 2009 Oct 8; 361(15):1448-58.(Link to article – subscription may be required.)