Mansonella perstans

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An organism that causes a form of filariasis that in man usually produces subclinical infection with microfilarial periodicity peaking in peripheral blood soon after sunrise.

Is is endemic in central and western Africa, with an intermediate midge (culicoides spp.) vector. Its infectivity is reduced by control measures targetted at its bacterial endosymbiont wolbachia[1] such as 6 weeks of doxycycline 200mg daily[2].