Methenamine silver staining

From Ganfyd

Grocott's staining of Pneumocystis jiroveci

Several histological stains use methenamine silver. Those used to highlight fungal organisms are based on Gömöri's original description, with subsequent modifications by Grocott's^[1] and others. This stains fungal organisms a brown/black on a green background (depending on counterstain used).

Periodic acid/methenamine silver staining of part of a glomerulus and surrounding tubules. The basement membranes of the glomerulus and the tubules are sharply stained black by the silver staining.

In combination with perioidic acid, it has been described as the Jones' staining method which is used more in renal histology to highlight collagen and the glomerular basement membranes. Also known as PAMS (periodic acid methenamine silver) or JMS (Jone's methenamine silver).

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