Methylphenidate

From Ganfyd

rINN: Methylphenidate

Other Names

Methylphenidate Hydrochloride, Ritalin^®, Concerta^® XL, Equasym XL^®

Pharmacological Information

Pharmacology Images

Methylphenidate Molecule

Methylphenidate in the:

BNF-registration required
BNF for children-registration required

DrugBank on Methylphenidate

PubDrug on Methylphenidate

UK SPCs of medicines with marketing authorisation

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Relevant Clinical Literature

Pubmed on Methylphenidate

NHS Evidence on Methylphenidate

RCT with Methylphenidate   from Pubmed

Systematic reviews   from Pubmed

TRIP Database on Methylphenidate

N Eng J Med, Lancet,JAMA, BMJ   from Pubmed

Cochrane Collaboration   from Pubmed

Google Scholar on Methylphenidate

Other Literature

PubChem on Methylphenidate

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Introduction

Clinical Use

Indications

• Attention deficit hyperactivity disorder
• Narcolepsy

Administration

Oral Child over 6 years 5mg od increasing to maximum 60mg in divided doses

Clinical Issues

Contra-indications

• Anxiety
• Tics
• Family history Torrette syndrome
• Hyperthyroidism
• Angina
• Arrhythmias
• Glaucoma

Cautions and Interactions

Side effects

• Neuroleptic malignant syndrome
• Irritability
• Alopecia
• Blood dyscrasia
• Cerebral arteritis
• Tics
• Angina
• Epilepsy
• Psychosis

Special advice

Pharmacology