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Used due to cautions when no better drug in:


It has recently been noted to have a small risk of severe liver injury, usually recovering, and of bullous skin eruptions eg Stevens-Johnson syndrome and toxic epidermal necrolysis(TEN). Also associated with prolongation of Q-T interval


Adverse Effects

  • Seizures (+/- predisposing condition)
  • Tendonitis
  • Arthropathy in immature animals - so avoided in children (except nalidixic acid) unless extenuating circumstances (only reversible musculoskeletal symptoms have been reported)
  • Photosensitivity
  • Acute kidney injury (association - doubles relative risk)
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