Omega-6 fatty acids
Omega-6 fatty acids is the popular name for n-6 polyunsaturated fatty acids. They are found in found in vegetable oils and nuts rather than fish oils as with longer chain omega-3 fatty acids and can be metabolised to anti-inflammatory or pro-inflammatory derivatives. The commonest are linoleic acid and arachidonic acid. There is some evidence that the n-6/n-3 ratio in the diet may constitute a predictor of low-grade inflammation and coagulation but also general evidence that diets higher in vegetable oils and nuts have net benefit suggesting the issue is perhaps overexposure to omega-6 relative to mega-3 fatty acids in the typical diet.
- In intermediate age related macular degeneration are likely to be ineffective or harmful compared to monosaturated fatty acids.
- ↑ Kalogeropoulos N, Panagiotakos DB, Pitsavos C, Chrysohoou C, Rousinou G, Toutouza M, Stefanadis C. Unsaturated fatty acids are inversely associated and n-6/n-3 ratios are positively related to inflammation and coagulation markers in plasma of apparently healthy adults. Clinica chimica acta; international journal of clinical chemistry. 2010 Apr 2; 411(7-8):584-91.(Link to article – subscription may be required.)
- ↑ Parekh N, Voland RP, Moeller SM, Blodi BA, Ritenbaugh C, Chappell RJ, Wallace RB, Mares JA. Association between dietary fat intake and age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS): an ancillary study of the Women's Health Initiative. Archives of ophthalmology. 2009 Nov; 127(11):1483-93.(Link to article – subscription may be required.)