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Common Name:N-acetylglucosamine-6-sulfatase
Other Names, such as IUPAC Name
Glucosamine-6-sulfatase, glucosamine (N-acetyl)-6-sulfatase, N-acetylglucosamine-G-sulfate sulfatase, glucosamine-6-sulphatase, G6S , EC:
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis
Wikipedia on N-acetylglucosamine-6-sulfatase (Less technical, ? quality control)

The GNS gene at 12q14.3 codes for N-acetylglucosamine-6-sulfatase.

Mutations cause mucopolysaccharidosis IIID (MPS IIID, Sanfilippo syndrome type D), explains up to 1/1,000,000 of the incidence of the mucopolysaccharidosis III phenotype. N-acetylglucosamine-6-sulfatase catalyses an essential step in the breakdown of heparan sulfate.