Web information on Pazopanib
Mechanism of Action
Relevant Clinical Literature
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Medpedia on Pazopanib (Less technical, good quality control)
Wikipedia on Pazopanib (Less technical, ? quality control)
A multikinase inhibitor that targets vascular endothelial growth factor receptors and showing promise for treating advanced renal cell carcinoma. It is also in development for other tumours such as soft-tissue sarcoma.
- ↑ Sternberg CN, Davis ID, Mardiak J, Szczylik C, Lee E, Wagstaff J, Barrios CH, Salman P, Gladkov OA, Kavina A, Zarbá JJ, Chen M, McCann L, Pandite L, Roychowdhury DF, Hawkins RE. Pazopanib in Locally Advanced or Metastatic Renal Cell Carcinoma: Results of a Randomized Phase III Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010 Jan 25.(Epub ahead of print) (Link to article – subscription may be required.)