Penicillin was discovered by Sir Alexander Fleming as a result of a laboratory slip up but he was unable to develop it for clinical use. Ten years later Ernst Boris Chain, Howard Florey (an Australian) and Norman Heatley developed it in time to save many lives during the Second World War. Because of the shortage of laboratory glassware milk bottles were used as culture media.
In 1945 Fleming, Florey and Chain were awarded the Nobel prize for medicine.
Intrathecal The correct doses for intra-thecal administration of Penicillin, in Meningitis and the like, are vastly smaller than intra-venous or other doses. Confusion between the two will result in disaster for patient and doctor.