Dipyridamole
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(Redirected from Persantin)
rINN: Dipyridamole
Other Names
Perstatin®
Pharmacological Information
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Web information on Dipyridamole
Relevant Clinical Literature
UK Guidance
Regulatory Literature
Other Literature
Please read pharmacological data limitations
Other Wikis
Medpedia on Dipyridamole (Less technical, good quality control)
Wikipedia on Dipyridamole (Less technical, ? quality control)
Contents |
Introduction
The prototype phosphodiesterase type 5 inhibitor which did not predict the interesting properties of its more selective successors. Long used with weak evidence base, perhaps because of its half life in peripheral vascular disease, it has fair evidence of effectiveness in secondary prevention of ischaemic stroke, and is useful in cardiac stress testing.
Clinical Use
Indications
- Antiplatelet agent
- Vasodilator increasing cardiac workload (iv)
Administration
Oral - Usual dose is modified release 200mg bd with low dose aspirin in secondary stroke prevention.
IV
Clinical Issues
Contra-indications
Cautions and Interactions
- Vasodilator
Side effects
- Headache is common.
- Risk of haemorrhage
