Plasmodium falciparum is the most important human cause of malaria as it is widespread and often life threatening. Its precursor evolved in Gorilla gorilla and then infected man. Its genome was sequenced in 2002. The female Anopheles mosquito is a usual vector and this explains why the disease transmission is mainly confined to areas of the world where the temperature is above 20C.
Symptoms of malaria typically begin 8-25 days following infection. In 2010 75% of the 219 million malaria cases were caused by it and it killed about 500,000 people. Control measures have reduced its worldwide incidence by about 30% from 2000 to 2015.
- Superkingdom Eukaryota
- ↑ Liu W, Li Y, Learn GH, Rudicell RS, Robertson JD, Keele BF, Ndjango JB, Sanz CM, Morgan DB, Locatelli S, Gonder MK, Kranzusch PJ, Walsh PD, Delaporte E, Mpoudi-Ngole E, Georgiev AV, Muller MN, Shaw GM, Peeters M, Sharp PM, Rayner JC, Hahn BH. Origin of the human malaria parasite Plasmodium falciparum in gorillas. Nature. 2010 Sep 23; 467(7314):420-5.(Link to article – subscription may be required.)
- ↑ Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3; 419(6906):498-511.(Link to article – subscription may be required.)