Plasmodium falciparum

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Plasmodium falciparum is the most important human cause of malaria as it is widespread and often life threatening. Its precursor evolved in Gorilla gorilla[1] and then infected man. Its genome was sequenced in 2002[2]. The female Anopheles mosquito is a usual vector and this explains why the disease transmission is mainly confined to areas of the world where the temperature is above 20C.

Symptoms of malaria typically begin 8-25 days following infection. In 2010 75% of the 219 million malaria cases were caused by it and it killed about 500,000 people. Control measures have reduced its worldwide incidence by about 30% from 2000 to 2015.