Primary sclerosing cholangitis

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Primary sclerosing cholangitis(PSC) is a cholestatic disorder of unknown aetiology, possibly autoimmune mediated. It results in patchy stricturing of the extra-hepatic bile ducts.

Association with inflammatory bowel disease (IBD). 70-80% of patients have IBD, while 2-4% of IBD patients have PSC.

Diagnosis

Treatments

None proven to significantly improve survival.

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