RET
From Ganfyd
Web Resources for RET
Genetic Databases
Relevant Clinical Literature
RCT with RET from Pubmed
UK Guidance
Rearranged during transfection protooncogene (RET, RET Protooncogene) is at 10q11.2
Mutations are found in multiple endocrine neoplasia type 2a and 2b
Codes a receptor tyrosine kinase.
Mutations can cause hirschsprung disease and are found in medullary thyroid carcinoma.
In papillary thyroid carcinoma a chimeric gene (RET/PTC1) formed through a somatic rearrangement involving the neighboring genes RET and CCDC6(H4, TST1, PTC1) is the oncogene.
