Rheumatoid factor

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Web Resources for Rheumatoid factor
Relevant Clinical Literature
Pubmed on Rheumatoid factor
RCT with Rheumatoid factor
Systematic reviews of Rheumatoid factor
Rheumatoid factor in N Eng J Med, Lancet, JAMA, BMJ
Rheumatoid factor in Cochrane Collaboration
TRIP Database on Rheumatoid factor
Google Scholar on Rheumatoid factor
Bandolier on Rheumatoid factor
UK Guidance
NHS Evidence on Rheumatoid factor
Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)
Nice Guidance on Rheumatoid factor
Prodigy Guidance on Rheumatoid factor
Other Wikis
Medpedia on Rheumatoid factor (Less technical, good quality control)
Wikipedia on Rheumatoid factor (Less technical, ? quality control)

Typically an IgM antibody to the Fc portion of IgG.

Seen in most cases of Rheumatoid arthritis but is also in other connective tissue diseases and in the elderly.

  • Method - A blood test

Tests -

Agglutination

  1. The agglutination of small latex beads coated with antibody
  2. The agglutination of sheep red blood cells coated with rabbit antibodies

Results are given as a titre

Info bulb.pngRheumatoid Factor is less useful than many people think. Its power to rule in a diagnosis is small, and its absence does not rule out Rheumatoid. (todo:figures)
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