Rifampicin
From Ganfyd
rINN: Rifampicin
Other Names
Rifadin®, Rimactane®
Pharmacological Information
Pharmacology Images
Web information on Rifampicin
Metabolism & Interactions
Inhibition of metabolism of other drugs metabolised by CYP2C8 has caused harm
Mechanism of Action
Rifamycin antibiotic
Other Issues for Rifampicin
Care with contact sensitivity, Also stains everything red
Relevant Clinical Literature
UK Guidance
Regulatory Literature
Other Literature
Please read pharmacological data limitations
Other Wikis
Medpedia on Rifampicin (Less technical, good quality control)
Wikipedia on Rifampicin (Less technical, ? quality control)
Rifamicin is a semisynthetic rifamycin derived from Amycolatopsis mediterranei. It was first marketed in 1966.
It has a useful range of activity allowing it to be used, usually in combination with a wide range of bacterial illness. It is a standard first line therapy for several infections including:
- Staphylococcus aureus
- Tuberculosis
- Brucellosis
- Buruli ulcer
- Meningococcal chemoprophylaxis
- Haemophilus influenzae chemoprophylaxis
- Legionnaire's disease
It has enzyme inducing properties so is used in cholestasis when patients are intolerant to colestyramine.
