Rituximab (MabThera®) is a monoclonal antibody directed against CD20, a cell surface receptor found on B cells. Used in treatment of non-Hodgkin's lymphoma in patients who are not fit enough for chemotherapy or have advanced disease.
- Relapsed/refractory follicular lymphoma responding to induction therapy with chemotherapy
- Stage III-IV follicular lymphoma in combination with chemotherapy
- CD20+ive diffuse large B cell non-Hodgkin's lymphoma in combination with CHOP chemotherapy
Cautions and Interactions
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