Selenium
From Ganfyd
Symbol: Se Atomic No: 34Selenium
Importance in Man of Selenium
Web Resources for Selenium
Relevant Clinical Literature
RCT with Selenium from Pubmed
UK Guidance
Selenium - Se . Element. Trace quantities are required for p53 gene activity. Varies in level according to place. Brazil nuts contain it.
 | There is no evidence to recommend selenium supplementation in those without a demonstrated deficiency state.[1] |
Deficiency is associated with cardiomyopathy, sometimes known toponymously as Keshan disease. Deficiency per se may not be responsible, but may make the individual more susceptible to viral infections.[2]. There are other potential associations of deficiency as with prostatic cancer[3].
Excess amounts may be associated with increased risk of type 2 diabetes[4].
Selenium sulphide is used as a lotion or shampoo for treatment for dandruff and fungal skin infections, e.g. tinea capitis or pityriasis versicolor.
References
- ↑ Schomburg L, Koehrle J. Selenium: benefits and risks. MMW Fortschritte der Medizin. 2007 Feb 22; 149(8):34-6.
- ↑ Levander OA, Beck MA. Interacting nutritional and infectious etiologies of Keshan disease. Insights from coxsackie virus B-induced myocarditis in mice deficient in selenium or vitamin E. Biological trace element research 1997;56(1):5-21.
- ↑ Brinkman M, Reulen RC, Kellen E, Buntinx F, Zeegers MP. Are men with low selenium levels at increased risk of prostate cancer? European journal of cancer (Oxford, England : 1990). 2006 Oct; 42(15):2463-71.(Link to article – subscription may be required.)
- ↑ Stranges S, Marshall JR, Natarajan R, Donahue RP, Trevisan M, Combs GF, Cappuccio FP, Ceriello A, Reid ME. Effects of Long-Term Selenium Supplementation on the Incidence of Type 2 Diabetes Ann Intern Med 2007; 147: 217-23
