Sertraline

From Ganfyd

rINN: Sertraline

Other Names

Lustral^®

Pharmacological Information

Pharmacology Images

Sertraline Molecule

Sertraline in the:

BNF-registration required
BNF for children-registration required

DrugBank on Sertraline

PubDrug on Sertraline

UK SPCs of medicines with marketing authorisation

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Mechanism of Action

Increases serotonergic neurotransmission.

Relevant Clinical Literature

Pubmed on Sertraline

NHS Evidence on Sertraline

RCT with Sertraline   from Pubmed

Systematic reviews   from Pubmed

TRIP Database on Sertraline

N Eng J Med, Lancet,JAMA, BMJ   from Pubmed

Cochrane Collaboration   from Pubmed

Google Scholar on Sertraline

Other Literature

PubChem on Sertraline

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Indication

• Depressive illness

Dose

Dose: 50-100mg daily

Side Effects

• Serotonin syndrome
• Bleeding (this risk is much enhanced in those on NSAIDs and aspirin)^[1]