The Substantia nigra is divided into the pars compacta which contains the composed of closely packed pigmented dopaminergic neurons that are affected in Parkinsonism and the pars reticularis. Its name comes from the dark colour of neuromelanin (brown pigment) which may well play a key role in its neurotoxin sensitivity. It projects to all areas of the striatum with important cortical input.
Substantia nigra is highlighted in brown in the images
|System:||Central nervous system|
|Function:||Motor pathway integration/output control.|
|Arterial supply:||Penetrating branches of posterior cerebral artery and posterior communicating artery|
|Innervation:||See Basal ganglia circuitry|
|Search for Substantia nigra in Gray's.|