Superficial thrombophlebitis was a condition with out licensed drug treatment until 2010 when fondaparinux for 45 days showed a reduction in complicating VTE events of 1%. This is very similar to the risk patients face at the end of current treatment regimes for first ever VTE events. It is possible that the insufficiently studied out of license use of NSAIDs and other usual treatments is more cost effective. Surgical intervention is sometimes used. There are associations such as with Behçet's syndrome or the migratory non varicose vein thrombophlebitis form associated with malignancy. Short courses of low molecular weight heparin are useless.
This article is a work in progress. Please feel free to contribute to it.
- ↑ Binder B, Lackner HK, Salmhofer W, Kroemer S, Custovic J, Hofmann-Wellenhof R. Association between superficial vein thrombosis and deep vein thrombosis of the lower extremities. Archives of dermatology. 2009 Jul; 145(7):753-7.(Link to article – subscription may be required.)
- ↑ Goldman L, Ginsberg J. Superficial phlebitis and phase 3.5 trials. The New England journal of medicine. 2010 Sep 23; 363(13):1278-80.(Link to article – subscription may be required.)
- ↑ Cesarone MR, Belcaro G, Agus G, Georgiev M, Errichi BM, Marinucci R, Errichi S, Filippini A, Pellegrini L, Ledda A, Vinciguerra G, Ricci A, Cipollone G, Lania M, Gizzi G, Ippolito E, Bavera P, Fano F, Dugall M, Adovasio R, Gallione L, Del Boccio G, Cornelli U, Steigerwalt R, Acerbi G, Cacchio M, Di Renzo A, Hosoi M, Stuard S, Corsi M, Di Ciano L, Simeone E, Collevecchio G, Grossi MG, Di Giambattista F, Carestia F, Zukowski A. Management of superficial vein thrombosis and thrombophlebitis: status and expert opinion document. Angiology. 2007 Apr-May; 58 Suppl 1:7S-14S; discussion 14S-15S.(Link to article – subscription may be required.)
- ↑ Uncu H. A comparison of low-molecular-weight heparin and combined therapy of low-molecular-weight heparin with an anti-inflammatory agent in the treatment of superficial vein thrombosis. Phlebology / Venous Forum of the Royal Society of Medicine. 2009 Apr; 24(2):56-60.(Link to article – subscription may be required.)