Sweet's syndrome
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(Redirected from Sweet syndrome)
Web Resources for Sweet's syndrome
Relevant Clinical Literature
UK Guidance
Other Wikis
Medpedia on Sweet's syndrome (Less technical, good quality control)
Wikipedia on Sweet's syndrome (Less technical, ? quality control)
Sweet's syndrome (Sweet syndrome, acute febrile neutrophilic dermatosis) was first described by Sweet in 1964
- Characterised by:
- An acute neutrophilic dermatosis accompanied by pyrexia.
- Debilitating well defined red or plum plaques or nodules. They may be pustular.
- Aetiology is often unknown, but in such cases it is possible that the syndrome is due to a hypersensitivity reaction leading to cytokine-mediated neutrophil activation and infiltration as it can be induced by G-CSF.
Usually encountered in three main patient groups:
- Those with malignancy (tumour-related or paraneoplastic)
- Those on medication (drug-induced)
- Those with no obvious cause (idiopathic or 'classic')
