Talk:Circulating nucleic acids in plasma and serum

From Ganfyd

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"The nucleic acid in question can be RNA, mitochondrial DNA or genomic DNA, but DNA is generally used as it is less labile than RNA." I think this could be more clear. I take it the different NAs are all likely to be there, in mixture, but we _measure_ DNA to _use_ as an index becuase iit is less labile than some? Midgley 23:09, 9 April 2008 (BST)

Pretty much. DNA is easier to handle. RNA is easily broken down by ubiquitous RNAses and most relevant techniques work best on DNA, e.g. PCR. Mark ong 23:22, 9 April 2008 (BST)
To be honest, I have no idea what the actual relative quantities are. In theory, you should see more copies of mRNA, but how much is released into the blood stream and how stable it is when it gets there, I don't know. Mark ong 23:26, 9 April 2008 (BST)