Telbivudine
From Ganfyd
rINN: Telbivudine
Other Names
Sebivo®
Pharmacological Information
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Web information on Telbivudine
Relevant Clinical Literature
UK Guidance
Regulatory Literature
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Please read pharmacological data limitations
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Medpedia on Telbivudine (Less technical, good quality control)
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Contents |
Introduction
Telbivudine is an antiviral.
Clinical Use
Indications
- Chronic hepatitis B in adult patients with:
- Compensated liver disease
- Evidence of viral replication
- Persistently elevated serum alanine aminotransferase (ALT)
- Histological evidence of acute inflammation and/or fibrosis
It is one of three antivirals, lamivudine, tenofovir and telbivudine that have evidence of safety and effectiveness in reducing hepatitis B load in pregnancy [1]. It appears to reduce vertical transmission in pregnancy[2].
Administration
Oral 600mg od
Clinical Issues
Contra-indications
Cautions and Interactions
Side effects
Special advice
Pharmacology
References
- ↑ Yogeswaran K, Fung SK. Chronic hepatitis B in pregnancy: unique challenges and opportunities. The Korean journal of hepatology. 2011 Mar; 17(1):1-8.(Link to article – subscription may be required.)
- ↑ Hana G, Caob M, Zhaoc W, Jianga H, Wanga C, Baia S, Yuea X, Wanga G, Tanga X, Zhi-Xunc F.A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection. J Hepatol 2011 doi:10.1016/j.jhep.2011.02.032
