Tumour necrosis factor alpha

From Ganfyd

Jump to: navigation, search
Tumour necrosis factor alpha is one of a number of cytokines of the tumor necrosis factor (TNF) superfamily, it is coded by the TNF gene at 6p21.3. It is released mainly from macrophages binding receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR on a wide range of cell types including cells involved in:

It is implicated as a factor in:

It may have a neuroprotective role.

New drugs including Etanercept which block TNF-alpha may be shown to be useful in a variety of conditions.

Personal tools