Tyrosine-protein kinase JAK1

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Common Name:Tyrosine-protein kinase JAK1
Other Names, such as IUPAC Name
Janus kinase 1 tyrosine kinase, Janus kinase 1, EC:2.7.10.2, JAK-1
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis
Medpedia on Tyrosine-protein kinase JAK1 (Less technical, good quality control)
Wikipedia on Tyrosine-protein kinase JAK1 (Less technical, ? quality control)

Tyrosine-protein kinase JAK1 is a 1154 amino acid non receptor protein coded by the JAK1 gene at 1p31.3 and is a key signalling protein.

Receptor associations

It is the kinase partner for the interleukin-2 receptor and is involved in the IFN-alpha/beta/gamma signal pathway.

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