Urine protein to creatinine ratio
A surrogate measure of urinary protein loss and a more convenient alternative to 24-hour urine collection.
The ratio of protein (in milligram) to creatinine (in mmol) in the urine approximates to the amount of protein. The approximate conversion ratio is that about x10, i.e. 50mg/mmol is equivalent to about 500mg/day of proteinuria. Values of 3g to 3.5g are regarded as nephrotic syndrome amounts.
- ↑ Ginsberg JM, Chang BS, Matarese RA, Garella S. Use of single voided urine samples to estimate quantitative proteinuria. The New England journal of medicine. 1983 Dec 22; 309(25):1543-6.(Link to article – subscription may be required.)
- ↑ Price CP, Newall RG, Boyd JC. Use of protein:creatinine ratio measurements on random urine samples for prediction of significant proteinuria: a systematic review. Clinical chemistry. 2005 Sep; 51(9):1577-86.(Link to article – subscription may be required.)