Voltage-dependent P/Q-type calcium channel subunit alpha-1A
From Ganfyd
(Redirected from Voltage-dependent N-type calcium channel subunit alpha-1A)
Common Name:Voltage-dependent P/Q-type calcium channel subunit alpha-1A
Other Names, such as IUPAC Name
Voltage-gated calcium channel subunit alpha Cav2.1, calcium channel, L type, alpha-1 polypeptide isoform, Brain calcium channel, BI
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis
Medpedia on Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Less technical, good quality control)
Wikipedia on Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Less technical, ? quality control)
The protein voltage-dependent P/Q-type calcium channel subunit alpha-1A is coded by the CACNA1A gene and if dysfunctional leads to:
- Spinocerebellar ataxia type 6 (SCA6)
- Familial hemiplegic migraine type 1
- Episodic ataxia type 2 (acetazolamide-responsive hereditary paroxysmal cerebellar ataxia)
It is part of a brain specific membrane protein that belongs to the high-voltage activated group of voltage-dependent calcium channels.
