Voltage-dependent P/Q-type calcium channel subunit alpha-1A
The protein voltage-dependent P/Q-type calcium channel subunit alpha-1A is coded by the CACNA1A gene and if dysfunctional leads to:
- Spinocerebellar ataxia type 6 (SCA6)
- Familial hemiplegic migraine type 1
- Episodic ataxia type 2 (acetazolamide-responsive hereditary paroxysmal cerebellar ataxia)
It is part of a brain specific membrane protein that belongs to the high-voltage activated group of voltage-dependent calcium channels.