Warthin's tumour

From Ganfyd

Also known as a papillary cystadenoma lymphomatosum or an adenolymphoma. The latter name describes the two histological components, but can cause confusion amongst inexperience clinicians who may assume it is a form of haematological malignancy.

Aetiology

• Seven times more frequently in men, some studies show a smaller
• Peak age of incidence is 70
• Up to 10% are bilateral

Pathology

Photomicrograph of a Warthin's tumour showing the mixture of glandular and lymphoid tissue.

Photomicrograph of a Warthin's tumour showing the biphasic appearance of glandular and lymphoid tissue.

Arise from heterotropic tissue in lymph nodes within the parotid gland. Cystic appearence.

Microscopically, the glandular elements are formed from bilayered columnar cells with eosinophilic cytoplasm (so called oncocytic appearance). Cystically dilated duct spaces and papillary areas can also be seen hence is alternative name of papillary cystadenoma lymphomatosum. The lymphoid tissue frequently shows follicle formation and consists of both B- and T-cells.

Surgery

• Same technique as for pleomorphic adenoma
• Much less likely to recur